Squamous cell carcinoma antigen (SCC ) Uses

Squamous cell carcinoma antigen (SCC ) is a glycoprotein of molecular weight ~ 45 kDa, belonging to the family of serine protease inhibitors of cysteine /. The protein was originally isolated by Kato and colleagues from human tissues and squamous cell carcinomas proved to have at least 10 different sub-fractions in isoelectric point. SCC antigen is a serologic marker of squamous cell carcinoma of the cervix, vulva, uterus, lung, head and neck, and esophagus . In case of squamous cell carcinoma of the cervix, serum pre SCC-ag treatment can be used as an early prognostic factors and the use of pretreatment SCC Ag was suggested to select patients at high risk for adjuvant therapy. In addition, for patients with levels high SCC AG before starting treatment, the profile of FA SCC correlates with response to radio-and chemo-therapy and the extent of ag NAC can be used to monitor the effect of treatment and early detection of recurrent disease.