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2011年8月11日星期四

What is Aconitine?


Aconitine is a highly toxic alkaloid from various species.It aconite is a neurotoxin that opens TTX-sensitive Na + channels in the heart and other tissues and is used to create models of cardiac arrhythmia. Aconitine has been used as an antipyretic and analgesic, and still has limited application in herbal medicine, although the narrow therapeutic index makes the calculation of the appropriate dose difficult.

Strong alkaloids, aconitine called after the name of the species are present in every part of the plant, but they are concentrated in the roots and seeds. Aconitine depressed heart rate, if eaten, it causes first a feeling like ants crawling on the skin, followed by numbness. At high doses it is fatal; with lower doses, it is used as a homeopathic remedy for restlessness, fear and sudden fever.

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